Which spinal plexus gives rise to the phrenic nerve and what organ does the nerve supply?

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Phrenic Nerve[edit | edit source]

Nội dung chính Show

  • Phrenic Nerve[edit | edit source]
  • Origin[edit | edit source]
  • Course[edit | edit source]
  • Supply[edit | edit source]
  • Phrenic Nerve Palsy[edit | edit source]
  • References[edit | edit source]
  • Which spinal plexus gives rise to the phrenic nerve and what organ does the nerve supply?
  • Which plexus gives rise to the phrenic nerve?
  • Where does the phrenic nerve exit the spinal cord quizlet?
  • Does the phrenic nerves arise from the cervical plexuses?

The phrenic nerve is among the most important nerves in the body due to its role in respiration. The phrenic nerve provides the primary motor supply to the diaphragm, the major respiratory muscle[1]. It passes motor information to the diaphragm and receives sensory information from it. There are two phrenic nerves, a left and a right one.[2]

Image 1: The Phrenic nerve, showing course to diaphragm.

Both of these nerves supply

  • Motor fibers to the diaphragm and
  • Sensory fibers to the fibrous pericardium, mediastinal pleura, and diaphragmatic peritoneum.[2]

Image: Right phrenic nerve (highlighted in green) - anterior view[3]

Origin[edit | edit source]

Image 1 showing origin of the Phrenic Nerve

The phrenic nerve originates mainly from the 4th cervical nerve, but also receives contributions from the 3rd and 5th cervical nerves (C3-C5) in humans.[4] Thus, the phrenic nerve receives innervation from parts of both the cervical plexus and the brachial plexus of nerves.

Course[edit | edit source]

In the neck, the phrenic nerve lies on the anterior surface of the anterior scalene muscle, passes over the dome of the pleura and enters the thorax posterior to the subclavian vein. The right and left phrenic nerves have a different course in the thorax but as a general rule they descend as lateral as possible whilst keeping in contact with the mediastinal pleura. Both travel anterior to the hilum/bronchus on their respective side.[5]

The right Phrenic nerve descends in the thorax along the right side of the right brachiocephalic vein and the superior vena cava. It passes in front of the root of the right lung and runs along the right side of the pericardium, which separates the nerve from the right atrium. It then descends on the right side of the inferior vena cava to the diaphragm.Its terminal branches pass through the caval opening in the diaphragm to supply the central part of the peritoneum on its under aspect. (Image 2)

Image 2 showing Right and Left Phrenic nerve supplying ipsilateral dome of the diaphragm

The left Phrenic nerve descends in the thorax along the left side of the left subclavian artery. It crosses the left side of the aortic arch and here crosses the left side of the left Vagus nerve. It passes in front of the root of the left lung and then descends over the left surface of the pericardium which separates the nerve from the left ventricle. On reaching the diaphragm, the terminal branches pierce the muscle and supply the central part of the peritoneum on its under aspect.(Image 2)[2]

Supply[edit | edit source]

The phrenic nerve is the sole motor supply to each hemidiaphragm. It also provides sensory supply to:

  • diaphragm (except the most peripheral diaphragm, which is supplied by intercostal nerves)
  • mediastinal pleura
  • pericardium
  • central parts of diaphragmatic pleura and peritoneum[5]

Phrenic Nerve Palsy[edit | edit source]

Phrenic nerve palsy (also known as phrenic nerve paresis or paralysis) has many causes and can be caused by lesions anywhere along the course of the phrenic nerve, as it travels from the neck, to pierce the diaphragm adjacent to the pericardium.

  • One common etiology of phrenic nerve injury is from surgery, primarily thoracic and cardiac surgery. The left phrenic nerve descends anteriorly between the pericardium and mediastinal pleura and can be injured while dissecting near the area of an internal thoracic artery.
  • The phrenic nerve can also be damaged from blunt or penetrating trauma, metabolic diseases eg diabetes, infectious causes eg Lyme disease and herpes zoster, direct invasion by tumor, neurological diseases such eg cervical spondylosis and multiple sclerosis, myopathy and immunological disease (e.g., Guillain-Barre syndrome)[1].
  • Spinal cord injury is another cause. Depending on which vertebrae are damaged, nerve impulses can be disrupted. It is more likely if the injury occurs above the third vertebrae. If the injury is lower in the spine, breathing is usually not impacted.

The diagnosis of phrenic nerve injury requires high suspicion due to nonspecific signs and symptoms including unexplained shortness of breath, recurrent pneumonia, anxiety, insomnia, morning headache, excessive daytime somnolence, orthopnea, fatigue, and difficulty weaning from mechanical ventilation. On physical examinations, findings may include decreased breath sounds on the affected side, dullness to percussion of the affected side of the chest and inward movement of the epigastrium during inspiration.

Most patients with asymptomatic unilateral diaphragmatic paralysis do not require treatment. Treatment options if required include:

  • Plication of the affected site is a very useful treatment method that allows weaning from mechanical ventilation. Plication is preferably performed in unilateral diaphragmatic paralysis in non-morbidly obese patients. Surgical plication stabilizeS the diaphragm to prevent the lungs from ballooning outward during expiration (breathing out).
  • Phrenic nerve stimulation.   Phrenic nerve stimulation is performed in intact phrenic nerve without evidence of myopathy. This procedure can be performed in patients with bilateral diaphragmatic paralysis with cervical spine injuries[1]
  • Phrenic nerve repair may also be considered in an attempt to restore function of the paralyzed hemidiaphragm and it may be the optimal first line treatment when feasible.[6]

References[edit | edit source]

  1. ↑ 1.0 1.1 1.2 Mandoorah S, Mead T. Phrenic nerve injury.2018 Available from: https://www.ncbi.nlm.nih.gov/books/NBK482227/(accessed 8.2.2021)
  2. ↑ 2.0 2.1 2.2 Prakash; Prabhu, L. V.; Madhyastha, S; Singh, G (2007). "A variation of the phrenic nerve: Case report and review"
  3. Right phrenic nerve (highlighted in green) - anterior view image - © Kenhub https://www.kenhub.com/en/library/anatomy/phrenic-nerve
  4. Moore, Keith L. (1999). Clinically oriented anatomy. Philadelphia: Lippincott Williams & Wilkins. ISBN 978-0-683-06141-3
  5. ↑ 5.0 5.1 Radiopedia Phrenic nerve Available from: https://radiopaedia.org/articles/phrenic-nerve (last accessed 8.2.2021)
  6. Kaufman MR, L. Bauer T. Surgical Treatment of Phrenic Nerve Injury. March 2019. doi:10.25373/ctsnet.7863332.Available from: https://www.ctsnet.org/article/surgical-treatment-phrenic-nerve-injury(accessed 8.2.2021)

Which spinal plexus gives rise to the phrenic nerve and what organ does the nerve supply?

Phrenic nerve

The phrenic nerve as it passes through the thorax to supply the diaphragm.

The phrenic nerve emerges from the cervical plexus, with the right brachial plexus shown here.

Details

From

C3–C5 of cervical plexus

Phrenic nerve - Wikipediaen.wikipedia.org › wiki › Phrenic_nervenull

Which plexus gives rise to the phrenic nerve?

The phrenic nerve is derived from the cervical plexus and receives innervation from the C3, C4, and C5 nerve roots. It is the longest branch of the cervical plexus.

Where does the phrenic nerve exit the spinal cord quizlet?

The phrenic nerve originates at the C3 through C5 nerve roots, which exits the spinal canal at the neck root and descends caudally, parallel to the pericardial sac to provide the motor innervation to the diaphragm.

Does the phrenic nerves arise from the cervical plexuses?

Origin. The phrenic nerve originates mainly from the 4th cervical nerve, but also receives contributions from the 3rd and 5th cervical nerves (C3-C5) in humans. Thus, the phrenic nerve receives innervation from parts of both the cervical plexus and the brachial plexus of nerves.

Which plexus gives rise to your phrenic nerve?

The phrenic nerve is derived from the cervical plexus and receives innervation from the C3, C4, and C5 nerve roots.

Which spinal nerves contribute to the phrenic nerve and what is its main function?

Your phrenic nerve connects to the C3 to C5 cervical (neck) nerve roots of your spinal cord. The nerve: Starts at the C3 vertebral level, the part that aligns with your jaw and helps you bend and rotate your neck.

What is innervated by the phrenic nerve which comes from the cervical plexus?

The deep branches of the cervical plexus innervate the deeper structures of the neck, including the muscles of the anterior neck and the diaphragm (phrenic nerve), and are not blocked for local anesthetic procedures.

Which of the following spinal nerve plexuses gives rise to the phrenic nerve controlling the skeletal muscle of the diaphragm?

1). The cervical plexus is composed of axons from spinal nerves C1 through C5 and branches into nerves in the posterior neck and head, as well as the phrenic nerve, which connects to the diaphragm at the base of the thoracic cavity.