Which hormones interact with membrane-bound receptors and does not normally enter the target cell

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Follicle stimulating hormone

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Solution

The correct option is C ProgesteroneHormones bind to certain proteins called hormone receptors which are present on the cell membrane of the target cells or inside the target cells. Lipid soluble hormones, which include steroid hormones and iodothyronines, can cross the cell membrane’s lipid bilayer and enter the target cell. They interact with intracellular receptors. Since progesterone is a steroid hormone, it can cross the cell. Water soluble hormones, which include those that are amino-acid derivatives, peptides, polypeptides and proteins, interact with membrane-bound receptors. This interaction produces second messengers, which regulate cellular metabolism. Epinephrine is an amino acid derivative hormone, and follicle stimulating hormone and prolactin are protein hormones. Therefore, these hormones cannot cross the cell membrane.

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Solution

The correct option is A Cyclic AMPCyclic AMP is the second messenger generated when hormone interacts with membrane-bound receptors and this in turn regulates cellular metabolism. The other three options are incorrect as insulin regulates glucose metabolism. T3 regulates the metabolic rate of the body and thus, helps in maintaining basal metabolic rate (BMR). Gastrin is a peptide hormone that stimulates the secretion of hydrochloric acid and pepsinogen.

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Which hormone interacts with membrane bound receptor and does not normally enter the target?

Cyclic adenosine monophosphate is termed the second messenger. The hormones which interact with membrane-bound receptors normally do not enter the target cell but generate second messengers (e.g., cAMP).

Which hormone interact with membrane bound receptors on a cell?

Steroid hormones are generally thought to pass easily across a plasma membrane into a cell, interacting once inside with soluble nuclear receptors, but recent experiments have demonstrated the importance of membrane-bound receptors in mediating the activity and the metabolism of steroid hormones.

Which one of the following hormone does not have membrane bound receptors?

On the other hand, steroid hormones like testosterone being hydrophobic molecules, diffuse freely into all cells and act within the cell. Thus they do not need cell membrane bound receptors, instead they have mobile receptor proteins in the cytoplasm.

Which of the following hormones will bind to a membrane receptor on its target cell and stimulates the generation of second messenger ?`?

So the correct answer is cyclic AMP.