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result from the ACTH or cortisol excess and manifests as exaggerated cortisol actions.
obesity,fat redistribution, central obesity, buffalo hump, moon face, changes in protein metabolism,muscle weakness/ wasting in extremities, fibroblasts inhibited, loss of collagen and connective tissue, thinning of skin, abdominal striae, easy bruising,poor wound healing, frequent skin infections,altered glucose metabolism,DM,
electrolyte imbalances, calcium malabsorption, osteoporosis, compression fractures,renal calculi, hypokalemia, hypertension [as K lost and Na retained], hirsutism, menses irregularities,
health Hx: history of pituitary, adrenal,pancreatic, or pulmonary tumor. frequent infections, GI bleeding, stress fractures, pain, changes in weight distribution and height, fatigue, weakness, bruising, skin infections, menstrual history, sexual function.
physical: V.S. behavior, appearance, fat distribution, face, skin, hair distribution, muscle size and strength and gait
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